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Hyperhidrosis (Excessive Sweating)
Treat hyperhidrosis with evidence-based treatments that actually work
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What is Hyperhidrosis?
Hyperhidrosis is a medical term for excessive sweating beyond that which is needed to maintain body temperature. There are two main forms of the condition: primary focal and generalized.
Primary Focal Hyperhidrosis
When sweating affects one or more specific areas such as the palms of the hands, soles of the feet, underarms, face, etc., it is called "focal" hyperhidrosis.
Generalized Hyperhidrosis
Sweating all over the body is known as generalized hyperhidrosis. Critically, someone can sweat from their hands, feet, underarms, and face and not have "generalized" hyperhidrosis; rather, this is called multifocal primary hyperhidrosis.
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How Common Is Hyperhidrosis?
Hyperhidrosis is more common than many people realize. Studies estimate that up to 5% of the population is affected, though the true number may be higher due to underdiagnosis and underreporting.
Primary hyperhidrosis often begins before age 25 and often has a genetic component (meaning that it may run in families.
Despite its prevalence, many individuals do not seek medical care, either because they are unaware that effective treatments exist or because they feel embarrassed discussing their symptoms.
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What Causes Excessive Sweating?
There are two causes of hyperhidrosis - "primary" meaning that it happens because of a dysfunction in your body or "secondary" meaning that it happens because of another cause (e.g., medical condition or medication).
Primary Hyperhidrosis
Primary hyperhidrosis is caused by overactivity of the sympathetic nervous system, which controls involuntary bodily functions including sweating. The sweat glands themselves are structurally normal but receive excessive signals to produce sweat. Triggers may include stress, heat, physical activity, or eating spicy food.
Secondary Hyperhidrosis
Secondary hyperhidrosis occurs as a result of another medical condition or medication. In these cases, sweating often affects larger areas of the body and may occur during sleep.
Types of Hyperhidrosis by Body Area
Hyperhidrosis can affect one or multiple regions of the body. Different areas may require different treatment approaches.
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Discover Treatments for Full-Body SweatingSweaty Everywhere (Primary Multifocal or Generalized Hyperhidrosis)
Some individuals experience excessive sweating across multiple body areas or the entire body. This pattern is more often associated with secondary causes but can also be primary multifocal hyperhidrosis. -
Learn More About Treating Sweaty HandsSweaty Hands (Palmar Hyperhidrosis)
Excessive sweating of the palms can interfere with everyday tasks such as writing, typing, gripping objects, or shaking hands. Many people report difficulty with school, work, or social situations due to constantly wet hands. -
Explore Solutions for Sweaty FeetSweaty Feet (Plantar Hyperhidrosis)
Sweaty feet can lead to discomfort, slipping inside shoes, foot odor, and skin problems such as fungal infections or maceration. Symptoms are often worse when wearing closed footwear. -
See Treatments for Sweaty UnderarmsSweaty Underarms
Underarm hyperhidrosis may cause visible sweat stains on clothing, frequent clothing changes, and social embarrassment. It is one of the most commonly treated forms of excessive sweating. -
Learn About Options for Facial SweatingSweaty Face & Head (Craniofacial Hyperhidrosis)
Sweating of the face and scalp is the least common, but it can be particularly distressing because it is difficult to conceal. It may interfere with makeup, glasses use, and professional interactions. -
See Treatment OptionsOther Areas
Other areas like the groin, buttocks, chest/breasts, and back can be affected as well. For larger areas, we recommend treating like full-body sweating.
Treatment Options for Hyperhidrosis
Treatment depends on the severity, body areas involved, and whether the condition is primary or secondary. The table below summarizes the most commonly used treatment options for hyperhidrosis.
| Treatment | How It Works | Best For | Body Areas | Effectiveness | Cost | Prescription Needed |
|---|---|---|---|---|---|---|
| Glycopyrrolate Tablets | Reduce nerve signals to sweat glands throughout the body | Moderate to severe or generalized hyperhidrosis | Multiple areas or whole body | High | Low | Yes |
| Prescription-Strength Antiperspirants | Aluminum temporarily blocks sweat glands where applied | Mild hyperhidrosis | One body area | High (when used for mild hyperhidrosis) | Low | Yes |
| Iontophoresis | Uses mild electrical current to temporarily block sweat glands | Palmar, plantar, and axillary hyperhidrosis | Hands, feet, underarms |
High for hands/feet Medium for underarms |
Medium | Yes |
| Botulinum Toxin Injections | Blocks nerve signals that activate sweat glands | Severe localized sweating | Underarms, hands, face | High | High | Yes |
| Surgical Options (ETS) | Interrupts sympathetic nerve pathways | Severe, treatment-resistant cases | Primarily hands | High but serious risks | Very high | No |
For personalized treatment recommendations, reach out to one of our hyperhidrosis treatment experts .
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Buy Glycopyrrolate TabletsGlycopyrrolate Tablets for Hyperhidrosis
What are Glycopyrrolate Tablets?
Glycopyrrolate tablets are a prescription medication used to treat excessive sweating (hyperhidrosis).
Where do they work?
As an oral medication, they work throughout your body, which means that they reduce sweat all over the body.
Will they work for me?
Glycopyrrolate tablets have been clinically shown to reduce sweating in 90% of patients, with an average of a 75% reduction in the volume of sweat. Our pharmacists work with you to find the correct dose for you.
Glycopyrrolate Clinical Trial Data
1
%
Patients saw improvement when using glycopyrrolate
1
%
Patients with "major" improvement within days
1
%
Average reduction in sweat following treatment
Glycopyrrolate Clinical Trial References:
Finding the Right Dose of Glycopyrrolate
Every patient is unique, and our doctors and pharmacists are here to help you find the right dose for you!
Starting Dose
We start all patients on the same dose:
- One 1mg tablet taken twice daily
- About 50% of our patients get significant relief and are maintained on this dose
Dose Adjustments
We increase the dose each month until you get the relief you are seeking:
- No fees for changing dose
- We charge the same price, regardless of dose
- No additional doctor visit or forms required
How Do I Increase the Dose?
Just let us know, however is easiest for you:
- Call us
- Email us
- Leave a message with our chat bot
FDA-Registered Manufacturer
Real Doctors & Pharmacists
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Buy Prescription AntiperspirantPrescription-Strength Antiperspirants for Hyperhidrosis
What does it mean to be "prescription strength"?
We use 20% aluminum chloride, which is only available with a prescription. This means that it is at least 33% stronger than anything you can buy over the counter.
Where do they work?
Antiperspirants treat excessive sweating wherever you apply them. They are a perfect option for mild hyperhidrosis in one body area. For more severe cases of hyperhidrosis or when it affects more than one body area, glycopyrrolate tablets are a better choice.
Will they work for me?
Antiperspirants are extensively studied in hyperhidrosis and can be used alone or in combination with glycopyrrolate tablets.
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Buy Iontophoresis DeviceFDA-Cleared Iontophoresis Device for Hyperhidrosis
How does iontophoresis work?
Iontophoresis uses a gentle electrical current to temporarily block sweat glands.
Which body areas are treated by iontophoresis?
Iontophoresis treats excessive sweating in the hands, feet, and underarms.
Will iontophoresis work for me?
Iontophoresis was found to be effective for 90+% of patients in clinical trials.
Real Experiences from Real Customers with Hyperhidrosis
Frequently Asked Questions About Hyperhidrosis
What is hyperhidrosis?
Hyperhidrosis is a medical condition that causes excessive sweating beyond what is needed to regulate body temperature. People with hyperhidrosis may sweat even when they are not hot or physically active. The condition can affect specific areas such as the hands, feet, underarms, or face, or it may involve the entire body.
Why do I sweat so much even when I am not hot?
Excessive sweating without heat or exertion is typically caused by overactive nerve signals that stimulate the sweat glands. In primary hyperhidrosis, this occurs without an underlying disease. Emotional stress, anxiety, or no identifiable trigger at all can provoke sweating episodes.
What causes hyperhidrosis?
Primary hyperhidrosis is caused by overactivity of the sympathetic nervous system and is not linked to another medical condition. Secondary hyperhidrosis occurs due to underlying conditions such as hormonal disorders, infections, diabetes, or medication side effects. Determining the cause is important for choosing appropriate treatment.
Is hyperhidrosis dangerous?
Hyperhidrosis itself is usually not life-threatening, but it can significantly affect quality of life and emotional well-being. In some cases, excessive sweating may indicate an underlying medical condition that requires evaluation, particularly if symptoms begin suddenly or occur during sleep.
Can hyperhidrosis go away on its own?
Primary hyperhidrosis typically does not resolve spontaneously and may persist for many years without treatment. However, symptoms can fluctuate over time. Secondary hyperhidrosis may improve if the underlying cause is treated.
What is the best treatment for hyperhidrosis?
The most appropriate treatment depends on the severity of symptoms, the areas affected, and whether sweating is localized or generalized. Options range from clinical-strength antiperspirants to oral medications, iontophoresis, injections, and in severe cases, surgical procedures. Many patients require a combination of treatments to achieve optimal control.
How do I stop sweating everywhere?
Generalized excessive sweating often requires systemic treatment rather than topical therapies alone. Because multiple body areas are affected, treatments that work throughout the body may be more effective than localized approaches. A healthcare professional can help determine the safest and most appropriate option.
Why do my hands and feet sweat so much?
Excessive sweating of the hands and feet is known as palmar and plantar hyperhidrosis. These areas contain a high density of sweat glands and are particularly sensitive to emotional stress and autonomic nervous system activity. Symptoms often begin in childhood or adolescence.
Does anxiety cause hyperhidrosis?
Anxiety and stress can worsen sweating, but primary hyperhidrosis is a neurologic condition rather than purely psychological. Many people experience sweating even in calm situations. The relationship between sweating and anxiety can become cyclical, with each worsening the other.
When should I see a doctor for excessive sweating?
Medical evaluation is recommended if sweating begins suddenly in adulthood, occurs during sleep, affects only one side of the body, or is accompanied by fever, weight loss, or other symptoms. You should also seek care if sweating interferes with daily life or does not improve with over-the-counter treatments.
Key Takeaways About Hyperhidrosis
- Hyperhidrosis is a medical condition that causes excessive sweating beyond what is needed for normal temperature regulation.
- It affects millions of people and can involve specific areas (hands, feet, underarms, face) or the entire body.
- The condition results from overactive nerve signals to otherwise normal sweat glands.
- Hyperhidrosis can significantly impact quality of life, including social confidence, work performance, and emotional well-being.
- Effective treatments are available, ranging from topical therapies to systemic medications and procedures.
- Many people experience meaningful relief once they receive appropriate evaluation and treatment.
Medical References & Sources
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International Hyperhidrosis Society. Iontophoresis for Excessive Sweating.
Available at: https://www.sweathelp.org/hyperhidrosis-treatments/iontophoresis.html -
Pariser DM, Ballard A. Topical therapies in hyperhidrosis care.
Dermatologic Clinics. 2014;32(4):485-490.
doi:10.1016/j.det.2014.06.001
Available at: https://pubmed.ncbi.nlm.nih.gov/25152341/ -
McAleer MA, Collins P. A study investigating the efficacy of tap water iontophoresis for palmar hyperhidrosis.
Clinical and Experimental Dermatology. 2014;39(3):337-339.
doi:10.1111/ced.12294
Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5705354/ -
Glaser DA, Hebert AA, Nast A, et al. Management of primary focal hyperhidrosis: An updated treatment algorithm.
Journal of the American Academy of Dermatology. 2017;76(4):736-745.
doi:10.1016/j.jaad.2016.11.042
Available at: https://www.jaad.org/article/S0190-9622(18)32224-2/pdf -
Solish N, Bertucci V, Dansereau A, et al. A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis.
Dermatologic Surgery. 2007;33(8):908-923.
doi:10.1111/j.1524-4725.2007.33192.x
Available at: https://pubmed.ncbi.nlm.nih.gov/17661933/ -
Hornberger J, Grimes K, Naumann M, et al. Recognition, diagnosis, and treatment of primary focal hyperhidrosis.
Journal of the American Academy of Dermatology. 2004;51(2):274-286.
doi:10.1016/j.jaad.2003.12.029
Available at: https://pubmed.ncbi.nlm.nih.gov/15280848/
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Contact UsContact Our Experts With Any Questions About Hyperhidrosis
- Reach out to us, and one of our pharmacists will contact you for a consultation
